I love this Mouse Party educational tool from the Genetic Science Learning Center at the University of Utah about how various types of drugs affect the brain. I hadn't seen anything quite like it before, and it made me want to go through and learn more about each little dysfunctional mouse. Plus, they're pretty cute, even if they are under the influence.
It's probably a little too cutesy for CME, but I'd love to see this type of creativity go into other online programs. If anyone has seen something along these lines that's tackling a topic in more complex ways, please let me know. I'd love to check it out.