According to this article in today's Washington Post, even FDA scientists gave a vote of no confidence to some of the drugs the agency approved. A snippet:
The survey of almost 400 scientists also found that a majority had significant doubts about the adequacy of federal programs to monitor prescription drugs once they are on the market, and that more than a third were not particularly confident of the agency's ability to assess the safety of a drug.
Thanks to Debra for the link!